4-Fluoro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine CAS 2223033-80-3
| CAS No. | 2223033-80-3 |
| Molecular Formula | C12H17BFNO3 |
| Molecular Weight | 253.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 253.08 g/mol gives 4-Fluoro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Fluoro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2223033-80-3), a certified reference material (molecular formula C12H17BFNO3, MW 253.08 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (C12H17BFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Fluoro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17BFNO3 |
| Molecular Weight | 253.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-2-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1083168-95-9)
- 5-Fluoro-6-methoxypyridine-3-boronic Acid Pinacol Ester (CAS 1310384-35-0)
- (3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methanol (CAS 1314143-65-1)
- (4-Fluoro-3-((4-hydroxypiperidin-1-yl)methyl)phenyl)boronic acid (CAS 1704063-91-1)
- (3-Fluoro-4-((4-hydroxypiperidin-1-yl)methyl)phenyl)boronic acid (CAS 1704063-99-9)
- (3-Fluoro-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)boronic acid (CAS 1704064-09-4)
- (2-Fluoro-4-((4-hydroxypiperidin-1-yl)methyl)phenyl)boronic acid (CAS 1704064-23-2)
- 3-Fluoro-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one (CAS 1706750-04-0)
Recommended Standards
- 4-Fluoro-2-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2839744-28-2)
- 5-(Iodomethyl)-4,4-dimethylpyrrolidin-2-one (CAS 2138562-21-5)
- 4-Chloro-2-phenylpyrimidine-5-carbonyl chloride (CAS 66206-81-3)
- 5-iodopyrazolo[1,5-a]pyrimidine (CAS 705262-65-3)
- N-((5-(Furan-2-carbonyl)thiophen-2-yl)methyl)furan-2-carboxamide (CAS 1797964-08-9)
- 2,2'-(2,5-Dihexyl-1,4-phenylene)bis(1,3,2-dioxaborolane) (CAS 883741-17-1)
- Methyl 5-amino-2-ethylbenzoate (CAS 103095-32-5)
- methyl 3-amino-3-(2,4-difluorophenyl)propanoate hydrochloride (CAS 1333750-44-9)
- N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)acetamide (CAS 144038-79-9)
- (2-Hydroxy-5-(methoxycarbonyl)phenyl)boronic acid (CAS 1229442-38-9)
- Resmetirom impurity 135 (CAS 3096249-74-7)
- Atriopeptin II (rat) (H-2110.0500) (CAS 89139-54-8)
- Quinoline-4-carbonitrile hydrochloride (CAS 1187932-06-4)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
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