n-Propyl-3,4-dihydro-2h-1,4-benzoxazine-2-carboxamide CAS 22244-18-4
| CAS No. | 22244-18-4 |
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
n-Propyl-3,4-dihydro-2h-1,4-benzoxazine-2-carboxamide (CAS 22244-18-4) is a high-purity analytical reference standard with the molecular formula C12H16N2O2 and a molecular weight of 220.27 g/mol.
n-Propyl-3,4-dihydro-2h-1,4-benzoxazine-2-carboxamide (C12H16N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-Phenylquinolin-7-amine (CAS 688005-14-3)
- Octahydrospiro[imidazolidine-4,5'-[4,7]methanoindene]-2,5-dione (CAS 59455-06-0)
- N-Phenylquinolin-6-amine (CAS 70682-98-3)
- PHERO26237 (CAS 50346-47-9)
- 5-Bromo-1'H,3H-[2,3'-biindol]-3-one (CAS 92967-81-2)
- Methyl 3-chloro-4-methylcarbanilate (CAS 22133-20-6)
- 3-Methyl-4-thiocyanatophenol (CAS 3774-54-7)
- 5-Bromo-3,3-difluoro-1-methyl-2,3-dihydro-1H-indol-2-one (CAS 1630906-88-5)
- (2S)-2-Amino-N-methyl-4-(methylsulfanyl)butanamide (CAS 68800-02-2)
- (S)-1-(2-Chlorophenyl)but-3-en-1-amine hydrochloride (CAS 1285696-19-6)
- 1-(1-Ethyl-3,5-dimethyl-1h-pyrazol-4-yl)ethan-1-amine (CAS 936940-41-9)
- (4,6-Dichloropyrimidin-5-yl)(4-methoxyphenyl)methanone (CAS 1245646-55-2)
- tert-Butyl ((1-(2-chloroacetyl)piperidin-4-yl)methyl)(ethyl)carbamate (CAS 1353966-87-6)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com