6-Chloro-3,4-dihydroisoquinolin-1(2H)-one CAS 22246-02-2
| CAS No. | 22246-02-2 |
| Molecular Formula | C9H8ClNO |
| Molecular Weight | 181.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-3,4-dihydroisoquinolin-1(2H)-one.
6-Chloro-3,4-dihydroisoquinolin-1(2H)-one (CAS 22246-02-2) is a high-purity analytical reference standard with the molecular formula C9H8ClNO and a molecular weight of 181.62 g/mol.
Based on its molecular formula C9H8ClNO, 6-Chloro-3,4-dihydroisoquinolin-1(2H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 181.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClNO |
| Molecular Weight | 181.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-14-6)
- 4-Chloro-7-methoxy-1H-indole (CAS 1000341-80-9)
- 4-Chloro-5-ethyl-7h-pyrrolo[2,3-d]pyrimidine (CAS 1004992-44-2)
- 4-Chloro-1-ethyl-1H-imidazo[4,5-c]pyridine (CAS 1025509-11-8)
- 6-Chloro-2-ethylbenzoxazole (CAS 1027019-12-0)
- 6-Chloro-1-methyl-1H-indazol-3-amine (CAS 1031927-22-6)
- 4-chloro-1-methyl-1H-1,3-benzodiazol-2-amine (CAS 1037670-19-1)
- 5-Chloro-2,3-dimethylimidazo[4,5-b]pyridine (CAS 1044770-63-9)
Recommended Standards
- 6-Chloro-2-methylisoindolin-1-one (CAS 58141-51-8)
- 6-Chloro-N-methyl-1H-benzo[d]imidazol-1-amine (CAS 40533-93-5)
- 6-Chloro-2-methyl-1H-benzo[d]imidazol-4-amine (CAS 501688-77-3)
- 7-Chloro-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridine (CAS 94220-39-0)
- 3-(2,4,6-Trifluorophenyl)acrylic acid (CAS 239795-59-6)
- Methyl 2-((2,5-dimethylphenyl)amino)-3-nitrobenzoate (CAS 566869-95-2)
- N,N-Diisopropyl-3-(oxiran-2-yl)-2-phenylquinoline-4-carboxamide (CAS 650607-41-3)
- 2-{1-[4-(methylsulfanyl)benzoyl]piperidin-2-yl}acetic acid (CAS 1179765-47-9)
- n-Butyl-4-chlorobenzamide (CAS 1455-99-8)
- 5-Oxaspiro[3.5]Nonan-7-amine (CAS 1823516-17-1)
- 2-(2,5-Dichlorophenoxy)propanehydrazide (CAS 869951-14-4)
- 4-Cyclopropoxy-N2,N2,N5-trimethylpyridine-2,5-dicarboxamide (CAS 1243391-46-9)
- Nonyl decanoate (CAS 42231-48-1)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com