3-(2,4,6-Trifluorophenyl)acrylic acid CAS 239795-59-6

Purity 97%+In StockPharmaceutical Standards
CAS No.239795-59-6
Molecular FormulaC9H5F3O2
Molecular Weight202.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2,4,6-Trifluorophenyl)acrylic acid CAS 239795-59-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 202.13 g/mol gives 3-(2,4,6-Trifluorophenyl)acrylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(2,4,6-Trifluorophenyl)acrylic acid (CAS 239795-59-6) is a high-purity analytical reference standard with the molecular formula C9H5F3O2 and a molecular weight of 202.13 g/mol.

The molecular framework of 3-(2,4,6-Trifluorophenyl)acrylic acid (C9H5F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(2,4,6-Trifluorophenyl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H5F3O2
Molecular Weight202.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

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