(2-Bromo-6-chloropyridin-4-yl)boronic acid CAS 2225154-90-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2225154-90-3
Molecular FormulaC5H4BBrClNO2
Molecular Weight236.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Bromo-6-chloropyridin-4-yl)boronic acid CAS 2225154-90-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(2-Bromo-6-chloropyridin-4-yl)boronic acid (CAS 2225154-90-3) is a high-purity analytical reference standard with the molecular formula C5H4BBrClNO2 and a molecular weight of 236.26 g/mol.

Structurally, (2-Bromo-6-chloropyridin-4-yl)boronic acid (C5H4BBrClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 236.26 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H4BBrClNO2
Molecular Weight236.26 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentCl/Br-containing
Nitrogen Atoms1

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