(5-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid CAS 2225154-87-8
| CAS No. | 2225154-87-8 |
| Molecular Formula | C9H9BF3NO2 |
| Molecular Weight | 230.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (5-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(5-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225154-87-8), molecular formula C9H9BF3NO2 and molecular weight 230.98 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (5-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (5-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H9BF3NO2 |
| Molecular Weight | 230.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyclopropyl Standards
- (2-Cyclopropyl-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 1446486-08-3)
- (2-Cyclopropyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225176-76-9)
- (5-Cyclopropyl-2-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225175-30-2)
- (6-Cyclopropyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225173-40-8)
- (2-Cyclopropyl-5-(pyrrolidin-1-yl)phenyl)boronic acid (CAS 2225172-09-6)
- (3-Cyclopropyl-5-(pyrrolidin-1-yl)phenyl)boronic acid (CAS 2225169-97-9)
- 1-Cyclopropyl-1-(3,4-dichlorophenyl)ethanol (CAS 1247496-38-3)
- 1-Cyclopropyl-1-(3,4-dichlorophenyl)ethan-1-ol (CAS 1379310-89-0)
Recommended Standards
- 3-Iodopyrazine-2-carbonitrile (CAS 1062608-54-1)
- 5-Iodopyrimidine-2-carbonitrile (CAS 1083329-46-7)
- 3-(Bromomethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 1609396-23-7)
- 5-Iodopyrazine-2-carbonitrile (CAS 1196154-95-6)
- 4-Phenyltetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 873383-88-1)
- 1-(2,6-Dibromo-4-(difluoromethoxy)phenyl)ethanone (CAS 1804881-94-4)
- 5-(trifluoromethoxy)pyridin-2-amine (CAS 1221171-88-5)
- 3-Chloro-4-fluorophenylzinc iodide solution (CAS 312624-19-4)
- N-Ethyl-3-fluoroaniline hydrochloride (CAS 1193388-08-7)
- H-Glu(OBzl)-OH (CAS 1676-73-9)
- rel-methyl (3R,4S)-4-(4-bromophenyl)pyrrolidine-3-carboxylate hydrochloride (CAS 1956380-68-9)
- 3-Bromo-4-bromomethyl-2-(trifluoromethyl)pyridine (CAS 1227587-21-4)
- 1-(4-Aminophenyl)-5-ethyl-1H-pyrazole-4-carboxamide (CAS 1172318-49-8)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
Why CATO?
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