(4-Chloro-5-cyclopropylpyridin-3-yl)boronic acid CAS 2225155-46-2
| CAS No. | 2225155-46-2 |
| Molecular Formula | C8H9BClNO2 |
| Molecular Weight | 197.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-Chloro-5-cyclopropylpyridin-3-yl)boronic acid.
CATO supplies (4-Chloro-5-cyclopropylpyridin-3-yl)boronic acid (CAS 2225155-46-2), a certified reference material (molecular formula C8H9BClNO2, MW 197.43 g/mol) for analytical method development and quality control.
(4-Chloro-5-cyclopropylpyridin-3-yl)boronic acid (C8H9BClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4-Chloro-5-cyclopropylpyridin-3-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9BClNO2 |
| Molecular Weight | 197.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (5-Chloro-2-cyclopropylpyridin-3-yl)boronic acid (CAS 2225179-43-9)
- 2-Chloro-5-cyclopropylpyridine-3-boronic acid (CAS 2121511-56-4)
- 2-chloro-4-(dichloromethyl)pyrimidine (CAS 1803566-44-0)
- 4-Chloro-1-(difluoromethyl)-3-nitro-1h-pyrazole (CAS 1245773-01-6)
- 3-Chloro-6-hydroxy-4-(trifluoromethyl)pyridine (CAS 109919-31-5)
- 3-Chloro-2,5,6-trifluoro-4-methoxypyridine (CAS 1184172-33-5)
- 2-Chloro-5-(trifluoromethyl)pyridin-3-ol (CAS 1196153-98-6)
- 4-Chloro-2-hydroxy-6-(trifluoromethyl)pyridine (CAS 1196154-31-0)
Recommended Standards
- 5-Bromo-3-(chloromethyl)-1,2,4-oxadiazole (CAS 155742-36-2)
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- 9-(Heptadecan-9-yl)-3,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 1268491-07-1)
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Why CATO?
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