(5-Cyclopentyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid CAS 2225171-85-5
| CAS No. | 2225171-85-5 |
| Molecular Formula | C11H13BF3NO2 |
| Molecular Weight | 259.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (5-Cyclopentyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid (C11H13BF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies (5-Cyclopentyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225171-85-5), a certified reference material (molecular formula C11H13BF3NO2, MW 259.03 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (5-Cyclopentyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13BF3NO2 |
| Molecular Weight | 259.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- Ethyl 1-cyclopentyl-1H-benzo[d][1,2,3]triazole-5-carboxylate (CAS 1845706-36-6)
- 3-Cyclopentyl-4-methyl-n-phenyl-2,3-dihydro-1,3-thiazol-2-imine (CAS 454237-73-1)
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Recommended Standards
- (4-(Pyrrolidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid (CAS 2256708-86-6)
- 2,3,6-Trifluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2813245-28-0)
- (4-(Pyrrolidin-1-yl)-3-(trifluoromethyl)phenyl)boronic acid (CAS 895543-04-1)
- 2-Trifluoromethyl-4-(pyrrolidino)phenylboronic acid (CAS 2225178-40-3)
- Methyl 4,6-dibromo-3-(methoxymethoxy)picolinate (CAS 1799434-69-7)
- (3Z)-3-{[1-(4-methylbenzenesulfonyl)-1H-indol-3-yl]methylidene}-2,3-dihydro-1H-indol-2-one (CAS 694437-74-6)
- 3,5-Dimethyl-1-[(2-methylphenyl)methyl]-1H-pyrazole-4-carboxylic acid (CAS 1154898-71-1)
- 4,4,5,5-Tetramethyl-2-neopentyl-1,3,2-dioxaborolane (CAS 2375382-33-3)
- dimethyl({[5-(propan-2-yloxy)-1H-indol-3-yl]methyl})amine (CAS 835619-46-0)
- 1,1-Dimethylethyl 4-[2-(2-aminoethoxy)ethyl]-1-piperazinecarboxylate (CAS 1181972-47-3)
- 1-(3,4-Dihydroxy-2-methoxyphenyl)ethanone (CAS 27829-93-2)
- 1,4-Bis(trifluoromethyl)-5H-pyridazino[4,5-b]indole (CAS 111888-15-4)
- 6-chloro-7-fluoro-indoline-2,3-dione (CAS 942493-23-4)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
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