(4-(Pyrrolidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid CAS 2256708-86-6
| CAS No. | 2256708-86-6 |
| Molecular Formula | C11H13BF3NO2 |
| Molecular Weight | 259.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-(Pyrrolidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid.
(4-(Pyrrolidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid (CAS 2256708-86-6) is a high-purity analytical reference standard with the molecular formula C11H13BF3NO2 and a molecular weight of 259.03 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (4-(Pyrrolidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 259.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4-(Pyrrolidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13BF3NO2 |
| Molecular Weight | 259.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Pyrrolidin Standards
- (2-(Pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 1704063-76-2)
- (3-(Pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 1704067-30-0)
- (4-(Pyrrolidin-1-yl)-3-(trifluoromethyl)phenyl)boronic acid (CAS 895543-04-1)
- (R)-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)benzoic acid (CAS 1388712-31-9)
- (R)-4-(pyrrolidin-2-yl)-2-(trifluoromethyl)benzoic acid (CAS 1388804-52-1)
- 2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzoic acid (CAS 865470-92-4)
- 1-(3-(Pyrrolidin-1-yl)pyrazin-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 1707594-91-9)
- 1-(3-(Pyrrolidin-1-yl)pyrazin-2-yl)-1H-imidazole-4-carboxylic acid (CAS 1710674-91-1)
Recommended Standards
- (5-Cyclopentyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225171-85-5)
- 6-Bromo-7-fluoro-1H-indazole-3-carboxylic acid (CAS 1956341-21-1)
- 2,3,6-Trifluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2813245-28-0)
- 6-Bromo-5-fluoro-1H-indazole-3-carboxylic acid (CAS 1956325-61-3)
- (αS)-2-Chloro-4-fluoro-α-methyl-benzenemethanol (CAS 911218-03-6)
- 5-(Trifluoromethyl)-2,3-dihydro-1-benzofuran-3-amine (CAS 1243205-10-8)
- 1-Ethyl-2-iodo-3-methylbenzene (CAS 175277-95-9)
- 4-(chloromethyl)-1,3-dimethyl-1H-pyrazole (CAS 1119833-69-0)
- 5-Bromo-6-fluoroisoquinolin-1(2H)-one (CAS 1367774-38-6)
- ethyl 4-aminocinnoline-3-carboxylate (CAS 206002-69-9)
- Chloroterpyridinepalladium(1+) chloride (CAS 60819-01-4)
- 2-(Pyrrolidine-2-carbonyl)-1,2,3,4-tetrahydroisoquinolin-7-ol hydrochloride (CAS 1334145-92-4)
- 2-(2-Chloroquinolin-4-yl)benzo[d]thiazole (CAS 790263-71-7)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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