(4-Chloro-5-methoxy-2-methylphenyl)boronic acid CAS 2225174-69-4
| CAS No. | 2225174-69-4 |
| Molecular Formula | C8H10BClO3 |
| Molecular Weight | 200.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 200.43 g/mol gives (4-Chloro-5-methoxy-2-methylphenyl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4-Chloro-5-methoxy-2-methylphenyl)boronic acid (CAS 2225174-69-4) is a high-purity analytical reference standard with the molecular formula C8H10BClO3 and a molecular weight of 200.43 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, (4-Chloro-5-methoxy-2-methylphenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (4-Chloro-5-methoxy-2-methylphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BClO3 |
| Molecular Weight | 200.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-4-methoxy-5-methylphenylboronic acid (CAS 1050509-76-6)
- (4-Chloro-2-(methoxymethyl)phenyl)boronic acid (CAS 1208318-89-1)
- 2-Chloro-3-ethoxyphenylboronic acid (CAS 1256345-57-9)
- (3-Chloro-5-ethoxyphenyl)boronic acid (CAS 1256345-73-9)
- (4-Chloro-3-(methoxymethyl)phenyl)boronic acid (CAS 1392415-54-1)
- 2-Chloro-5-methoxymethylphenylboronic acid (CAS 1451392-23-6)
- 5-Chloro-6-(dimethylamino)pyridin-3-ylboronic acid (CAS 1704121-36-7)
- (2-Chloro-4-isopropylpyrimidin-5-yl)boronic acid (CAS 2225180-56-1)
Recommended Standards
- (4-Chloro-2-propylpyrimidin-5-yl)boronic acid (CAS 2225177-29-5)
- (5-Chloro-2-ethoxyphenyl)boronic acid (CAS 352534-86-2)
- (4-Chloro-2-isopropylpyrimidin-5-yl)boronic acid (CAS 2225174-09-2)
- (5-Chloro-4-methoxy-2-methylphenyl)boronic acid (CAS 511295-09-3)
- α-Cyclocitral (CAS 432-24-6)
- Methyl 3-bromo-4-cyano-2-methylbenzoate (CAS 1805519-96-3)
- ((2-(Chloromethoxy)ethoxy)methyl)benzene (CAS 31383-67-2)
- 4-Ethoxy-2,5-dimethylaniline (CAS 706822-63-1)
- 2-Bromo-1-(5-bromo-2,3-dihydrobenzofuran-7-yl)ethan-1-one (CAS 690632-70-3)
- Epinephrine Impurity 21 (CAS 16899-83-5)
- 3-Chlorotetrahydro-2H-pyran-2-ol (CAS 1003-57-2)
- N-((1-Isobutyl-1H-pyrazol-4-yl)methyl)-N-methylpiperidin-4-amine (CAS 2140316-96-5)
- Potassium bis(2-ethylhexyl) phosphate (CAS 4971-46-4)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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