(2-(3-Fluorophenyl)pyrimidin-5-yl)boronic acid CAS 2225176-72-5
| CAS No. | 2225176-72-5 |
| Molecular Formula | C10H8BFN2O2 |
| Molecular Weight | 217.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, (2-(3-Fluorophenyl)pyrimidin-5-yl)boronic acid (C10H8BFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 217.99 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(2-(3-Fluorophenyl)pyrimidin-5-yl)boronic acid (CAS 2225176-72-5), molecular formula C10H8BFN2O2 and molecular weight 217.99 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2-(3-Fluorophenyl)pyrimidin-5-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8BFN2O2 |
| Molecular Weight | 217.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- (2-(2-Fluorophenyl)pyrimidin-5-yl)boronic acid (CAS 2225172-10-9)
- (2-(4-Fluorophenyl)pyrimidin-5-yl)boronic acid (CAS 2225176-38-3)
- 2-(4-Fluorophenyl)pyrimidine-4-carboxylic acid (CAS 1092300-73-6)
- 6-(3-Fluorophenyl)pyrimidine-4-carboxylic acid (CAS 1207724-59-1)
- 4-(3-Fluorophenyl)-3-nitropyridine (CAS 1292369-68-6)
- 2-(3-Fluorophenyl)pyrimidine-4-carboxylic acid (CAS 1315364-03-4)
- 4-(4-Fluorophenyl)pyrimidine-2-carboxylic acid (CAS 1491142-21-2)
- 2-(4-Fluorophenyl)-3-nitropyridine (CAS 168267-36-5)
Recommended Standards
- (3-Ethyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225179-96-2)
- CAS 112370-55-5 (CAS 112370-55-5)
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