tert-Butyl N-{[(3R)-1-(5-bromo-2-chloropyrimidin-4-yl)piperidin-3-yl]methyl}carbamate CAS 2227197-43-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2227197-43-3
Molecular FormulaC15H22BrClN4O2
Molecular Weight405.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl N-{[(3R)-1-(5-bromo-2-chloropyrimidin-4-yl)piperidin-3-yl]methyl}carbamate CAS 2227197-43-3 chemical structure

Description

As a certified reference material (CRM), tert-Butyl N-{[(3R)-1-(5-bromo-2-chloropyrimidin-4-yl)piperidin-3-yl]methyl}carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

tert-Butyl N-{[(3R)-1-(5-bromo-2-chloropyrimidin-4-yl)piperidin-3-yl]methyl}carbamate (CAS 2227197-43-3) is a high-purity analytical reference standard with the molecular formula C15H22BrClN4O2 and a molecular weight of 405.72 g/mol.

tert-Butyl N-{[(3R)-1-(5-bromo-2-chloropyrimidin-4-yl)piperidin-3-yl]methyl}carbamate (C15H22BrClN4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC15H22BrClN4O2
Molecular Weight405.72 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentCl/Br-containing
Nitrogen Atoms4

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