N-(4-Chlorobenzyl)-5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-amine CAS 337928-15-1

Purity 97%+In StockPharmaceutical Standards
CAS No.337928-15-1
Molecular FormulaC17H10ClF6N3
Molecular Weight405.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Chlorobenzyl)-5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-amine CAS 337928-15-1 chemical structure

Description

N-(4-Chlorobenzyl)-5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-amine (CAS 337928-15-1), molecular formula C17H10ClF6N3 and molecular weight 405.72 g/mol, is a CATO reference standard with documented purity and traceability.

N-(4-Chlorobenzyl)-5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-amine (C17H10ClF6N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC17H10ClF6N3
Molecular Weight405.72 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms3

Related N Standards

Recommended Standards

Why CATO?