Tert-butyl (1R,3R,5R)-3-(bromomethyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylate CAS 2227198-68-5

Purity 97%+In StockPharmaceutical Standards
CAS No.2227198-68-5
Molecular FormulaC11H18BrNO2
Molecular Weight276.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl (1R,3R,5R)-3-(bromomethyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylate CAS 2227198-68-5 chemical structure

Description

The occurrence of Tert-butyl (1R,3R,5R)-3-(bromomethyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Tert-butyl (1R,3R,5R)-3-(bromomethyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylate (CAS 2227198-68-5), a certified reference material (molecular formula C11H18BrNO2, MW 276.17 g/mol) for analytical method development and quality control.

Tert-butyl (1R,3R,5R)-3-(bromomethyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylate (C11H18BrNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Tert-butyl (1R,3R,5R)-3-(bromomethyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H18BrNO2
Molecular Weight276.17 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentBr-containing
Nitrogen Atoms1

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