Febuxostat impound 107 CAS 2227293-69-6
| CAS No. | 2227293-69-6 |
| Molecular Formula | C12H11NO3S |
| Molecular Weight | 249.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Febuxostat impound 107 (CAS 2227293-69-6), a pharmacopoeial impurity reference standard (molecular formula C12H11NO3S, MW 249.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Febuxostat impound 107 (C12H11NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 249.29 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Febuxostat impound 107 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3S |
| Molecular Weight | 249.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Febuxostat Standards
- Febuxostat impurity 108 (CAS 1267681-15-1)
- Febuxostat Impurity 21 (CAS 407582-48-3)
- Febuxostat Impurity 33 (CAS 100118-38-5)
- Febuxostat Impurity 40 (CAS CATO-C4X-116240)
- Febuxostat impurity 130 (CAS CATO-C4X-1162106)
- Febuxostat Impurity 18 (CAS 1312815-35-2)
- Febuxostat Impurity 30 (CAS CATO-C4X-116230)
- Febuxostat impurity 127 (CAS CATO-C4X-1162103)
Recommended Standards
- (R)-(4-(cyclopropylsulfonyl)-1-nitrosopiperazin-2-yl)methanol (CAS CATO-C3D-262542)
- 1491AF 2-(3-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid 879636-95-0 C12H11NO3S (CAS 879636-95-0)
- Sulfasalazine EP Impurity J (CAS 144-83-2)
- 442531-30-8 4-Methoxy-3-[(1H-1,2,4-triazol-3-ylsulfanyl)methyl]benzaldehyde MFCD03021420 (CAS 442531-30-8)
- Dexamethasone Impurity 127 (CAS CATO-C4X-1165127)
- Zopiclone impurity 28 (CAS 69433-07-4)
- Pitolisant impurity 30 (CAS CATO-C4X-252030)
- 5α-Pregnan-17α¸21-diol-3¸11¸20-trione-1¸2¸4¸5-d4 (CAS 1482-51-5)
- 2-(Dimethylamino)thiazole-4-carboxylic acid (CAS 787548-84-9)
- Cyclohexanethiol, gold(1+) salt (1:1) (CAS 52673-84-4)
- 4-(4-Iodo-1h-pyrazol-1-yl)benzaldehyde (CAS 1340091-32-8)
- Methyl (2S,3S)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylate (CAS 1509941-50-7)
- (R)-1-(5-Methylfuran-2-yl)ethanamine (CAS 473733-22-1)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com