Dexamethasone Impurity 127 CAS CATO-C4X-1165127
| CAS No. | CATO-C4X-1165127 |
| Molecular Formula | C23H30BrClO5 |
| Molecular Weight | 501.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Dexamethasone Impurity 127 (CAS CATO-C4X-1165127, C23H30BrClO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H30BrClO5, Dexamethasone Impurity 127 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 501.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Dexamethasone Impurity 127 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H30BrClO5 |
| Molecular Weight | 501.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Dexamethasone Standards
- Dexamethasone 21-Iodide (CAS 2029-18-7)
- Dexamethasone Impurity 16 (CAS 55541-30-5)
- Dexamethasone Impurity 84 (CAS CATO-C4X-116584)
- Dexamethasone Impurity 87 (CAS CATO-C4X-116587)
- Dexamethasone Isonicotinate (CAS 2265-64-7)
- Dexamethasone Impurity 113 (CAS CATO-C4X-1165113)
- Dexamethasone Hemisuccinate (CAS 3800-86-0)
- Dexamethasone Impurity 114 (CAS CATO-C4X-1165114)
Recommended Standards
- Lumefantrine impurity 7 (CAS CATO-C4X-24267)
- DroMetrizole Trisiloxane (CAS 155633-54-8)
- 2-((2-((4-Chlorophenyl)sulfonamido)phenyl)thio)-N-(2,4-dichlorophenyl)acetamide (CAS 477869-03-7)
- (2Z)-3-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}-2-[5-(4-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile (CAS 338966-78-2)
- Ozagrel Impurity 42 (CAS CATO-C4X-197142)
- Bifonazole EP Impurity A (CAS 7598-80-3)
- Estradiol Benzoate EP Impurity D (CAS 983-30-2)
- Ethyl 2-{[2-(4-methoxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}acetate (CAS 100064-06-0)
- 3-(1-Ethyl-1h-1,2,4-triazol-5-yl)-2,2-dimethylpropanoic acid (CAS 1495827-09-2)
- 2-Bromo-5-(chloromethyl)thiophene (CAS 7311-46-8)
- 4-(Butylamino)quinazolin-8-ol (CAS 104742-93-0)
- Beta-Elemonic Acid (CAS 28282-25-9)
- Tert-butyl (4-((2-hydroxyethyl)amino)cyclohexyl)(methyl)carbamate (CAS 1353986-27-2)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com