Vortioxetine Impurity 132 HBr CAS 2228086-73-3
| CAS No. | 2228086-73-3 |
| Molecular Formula | C18H22N2OS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Vortioxetine Impurity 132 HBr (CAS 2228086-73-3, C18H22N2OSHBr) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution, Vortioxetine Impurity 132 HBr is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 395.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Vortioxetine Impurity 132 HBr under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H22N2OS HBr |
| Molecular Weight | 395.36 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 63 (CAS 1009-85-4)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 116 (CAS 102439-46-3)
- Vortioxetine Impurity 88 (CAS 103-19-5)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 48 (CAS 105456-67-5)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
Recommended Standards
- Lesinurad Impurity 6 (CAS CATO-C4X-14786)
- Elobixibat Impurity 38 (CAS CATO-C4X-283838)
- Eplerenone Impurity 39 (CAS CATO-C4X-163039)
- 2-Isonicotinoylhydrazine-1-carboximidamide (CAS 4427-16-1)
- 1-(4-CHlorophenoxy)-3-methyl-benzene (CAS 96028-10-3)
- 5-((1h-Pyrazol-1-yl)methyl)-2-chlorothiazole (CAS 453557-78-3)
- 4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)pyrimidine-5-carboxylic acid (CAS 1710194-79-8)
- Sunitinib Impurity 77 (CAS CATO-C4X-133377)
- Benzyl 2-(methylamino)acetate hydrochloride (CAS 40298-32-6)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com