Sunitinib Impurity 77 CAS CATO-C4X-133377
| CAS No. | CATO-C4X-133377 |
| Molecular Formula | C24H14F3N3O3 |
| Molecular Weight | 449.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 449.38 g/mol gives Sunitinib Impurity 77 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Sunitinib Impurity 77 (CAS CATO-C4X-133377) is a certified pharmaceutical impurity reference standard with the molecular formula C24H14F3N3O3 and a molecular weight of 449.38 g/mol.
Structurally, Sunitinib Impurity 77 (C24H14F3N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 449.38 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sunitinib Impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H14F3N3O3 |
| Molecular Weight | 449.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sunitinib Standards
- Sunitinib Impurity 79 (CAS CATO-C4X-133379)
- Sunitinib Impurity 90 (CAS CATO-C4X-133390)
- Sunitinib Impurity 70 (CAS CATO-C4X-133370)
- Sunitinib Impurity 59 (CAS CATO-C4X-133359)
- Sunitinib Impurity 64 (CAS CATO-C4X-133364)
- Sunitinib Impurity 2 (CAS 356068-99-0)
- Sunitinib Impurity 74 (CAS CATO-C4X-133374)
- Sunitinib Impurity 81 (CAS CATO-C4X-133381)
Recommended Standards
- 6-{[(4-bromophenyl)sulfanyl]methyl}-2-{[(4-methoxyphenyl)methyl]sulfanyl}pyrimidin-4-ol (CAS 866143-65-9)
- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chromenylium (CAS 47705-70-4)
- Bictegravir (CAS 1611493-60-7)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-[2-(trifluoromethyl)phenyl]acetamide (CAS 1775503-29-1)
- Bumetanide Impurity 48 (CAS CATO-C4X-198648)
- Pantoprazole Impurity 70 (CAS CATO-C4X-139970)
- Rimegepant Impurity 127 (CAS CATO-C4X-2487127)
- 1-(4-bromo-2-hydroxyphenyl)-2-(4-fluorophenyl)ethan-1-one (CAS 1803599-84-9)
- (4A'R,8a'R)-4',4a'-dihydrospiro[cyclohexane-1,2'-pyrano[3,2-d][1,3]dioxin]-8'(8a'H)-one (CAS 2165682-98-2)
- 2-Methoxy-5-(pentafluoro-lambda6-sulfanyl)benzamide (CAS 1706430-65-0)
- 169783-76-0 (3R,4R,5R)-4-Deuteriooxane-2,3,4,5-tetrol (CAS 169783-76-0)
- 25-Hydroxycholesterol-26,26,26,27,27,27-d6 (CAS 88247-69-2)
- Terlipressin Impurity 30 (CAS CATO-C4X-219330)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com