2-Amino-5-iodo-6-methylpyrimidin-4(3H)-one CAS 22294-57-1
| CAS No. | 22294-57-1 |
| Molecular Formula | C5H6IN3O |
| Molecular Weight | 251.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-5-iodo-6-methylpyrimidin-4(3H)-one (CAS 22294-57-1), molecular formula C5H6IN3O and molecular weight 251.03 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-5-iodo-6-methylpyrimidin-4(3H)-one (C5H6IN3O) contains an amide group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6IN3O |
| Molecular Weight | 251.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-4-iodo-6-methoxypyrimidine (CAS 100594-13-6)
- 5-Amino-4-iodo-2-methylpyridazin-3(2H)-one (CAS 1706451-96-8)
- 4-Amino-6-bromo-5-(difluoromethyl)picolinaldehyde (CAS 1804450-12-1)
- 4-Amino-3-bromo-5-(difluoromethyl)picolinaldehyde (CAS 1804450-18-7)
- 4-Amino-2-bromo-6-(difluoromethyl)nicotinaldehyde (CAS 1805053-81-9)
- 4-Amino-3-bromo-6-(difluoromethyl)picolinaldehyde (CAS 1805053-85-3)
- 4-Amino-2-bromo-5-(difluoromethyl)nicotinaldehyde (CAS 1805264-21-4)
- 6-Amino-5-bromo-3-(difluoromethyl)picolinaldehyde (CAS 1805335-55-0)
Recommended Standards
- 2-Amino-5-iodo-4-methoxypyrimidine (CAS 89322-66-7)
- 4-Iodo-2-methylpyrazole-3-carboxamide (CAS 292855-29-9)
- 2-Amino-4-bromo-3,6-difluorobenzamide (CAS 2820537-80-0)
- 6-Amino-5-iodo-2-methylpyrimidin-4(3H)-one (CAS 408326-41-0)
- 4-Bromo-3,5-dichloro-2-(difluoromethyl)pyridine (CAS 1806819-65-7)
- Ethyl 4-benzoyl-1h-pyrrole-2-carboxylate (CAS 119647-84-6)
- (R)-Methyl 2-(3-(chloromethyl)phenoxy)butanoate (CAS 1139688-50-8)
- 1-([1,1'-Biphenyl]-4-yl)-2-aminoethan-1-one (CAS 51127-68-5)
- 2,6-Dibromo-3-(2-(2,4-dichlorophenoxy)ethoxy)pyridine (CAS 1355026-47-9)
- tert-Butyl N-[1-(4-aminophenyl)azetidin-3-yl]carbamate (CAS 889948-10-1)
- (4-methoxyphenyl)diphenylphosphine oxide (CAS 795-44-8)
- (S)-3-Benzyl-1-methyl-piperazine dihydrochloride (CAS 1965305-43-4)
- 2-azido-1,3-thiazole (CAS 58822-97-2)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
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