6-Amino-5-iodo-2-methylpyrimidin-4(3H)-one CAS 408326-41-0
| CAS No. | 408326-41-0 |
| Molecular Formula | C5H6IN3O |
| Molecular Weight | 251.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Amino-5-iodo-2-methylpyrimidin-4(3H)-one (CAS 408326-41-0), molecular formula C5H6IN3O and molecular weight 251.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Amino-5-iodo-2-methylpyrimidin-4(3H)-one (C5H6IN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 6-Amino-5-iodo-2-methylpyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6IN3O |
| Molecular Weight | 251.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-4-iodo-6-methoxypyrimidine (CAS 100594-13-6)
- 5-Amino-4-iodo-2-methylpyridazin-3(2H)-one (CAS 1706451-96-8)
- 4-Amino-6-bromo-5-(difluoromethyl)picolinaldehyde (CAS 1804450-12-1)
- 4-Amino-3-bromo-5-(difluoromethyl)picolinaldehyde (CAS 1804450-18-7)
- 4-Amino-2-bromo-6-(difluoromethyl)nicotinaldehyde (CAS 1805053-81-9)
- 4-Amino-3-bromo-6-(difluoromethyl)picolinaldehyde (CAS 1805053-85-3)
- 4-Amino-2-bromo-5-(difluoromethyl)nicotinaldehyde (CAS 1805264-21-4)
- 6-Amino-5-bromo-3-(difluoromethyl)picolinaldehyde (CAS 1805335-55-0)
Recommended Standards
- 4-Iodo-2-methylpyrazole-3-carboxamide (CAS 292855-29-9)
- Methyl 5-Bromo-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate (CAS 30825-88-8)
- 2-Amino-5-iodo-6-methylpyrimidin-4(3H)-one (CAS 22294-57-1)
- N-(4,6-dichloro-5-nitropyrimidin-2-yl)acetamide (CAS 56145-04-1)
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