2-Chloro-N-(naphthalen-1-yl)propanamide CAS 22302-58-5
| CAS No. | 22302-58-5 |
| Molecular Formula | C13H12ClNO |
| Molecular Weight | 233.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-N-(naphthalen-1-yl)propanamide (C13H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Chloro-N-(naphthalen-1-yl)propanamide (CAS 22302-58-5) is a high-purity analytical reference standard with the molecular formula C13H12ClNO and a molecular weight of 233.69 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-N-(naphthalen-1-yl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO |
| Molecular Weight | 233.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1,1'-Bi[2-naphthoic acid] (CAS 99827-46-0)
- n-(2-(Isopropyl(methyl)amino)ethyl)-2-methyl-1,2,3,4-tetrahydroquinoline-4-carboxamide (CAS 1355789-17-1)
- 3-Bromo-4-(4-methylpiperidin-1-yl)benzaldehyde (CAS 1698473-77-6)
- N-[(2-Chlorophenyl)methyl]-1H-pyrrole-2-carboxamide (CAS 478249-65-9)
- methyl 2-(chlorosulfonyl)-4-nitrobenzoate (CAS 154712-47-7)
- 2-(2-Oxopropyl)malononitrile (CAS 121624-58-6)
- (5-Bromo-6-methylpyridin-3-yl)methanol (CAS 1174028-23-9)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
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