1,1'-Bi[2-naphthoic acid] CAS 99827-46-0
| CAS No. | 99827-46-0 |
| Molecular Formula | C22H14O4 |
| Molecular Weight | 342.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,1'-Bi[2-naphthoic acid] (CAS 99827-46-0), molecular formula C22H14O4 and molecular weight 342.34 g/mol, is a CATO reference standard with documented purity and traceability.
1,1'-Bi[2-naphthoic acid] (C22H14O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H14O4 |
| Molecular Weight | 342.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
Related Bi Standards
- 2-Naphthoic anhydride (CAS 20176-11-8)
- 1-Phenyl-2-naphthoic acid (CAS 85679-03-4)
- 6-Phenyl-2-naphthoic acid (CAS 855207-53-3)
- Naphthoic Acid Related Compound 4 (CAS 18012-57-2)
- 4-Propyl-1-naphthoic Acid (CAS 107777-22-0)
- 4-Acetyl-1-naphthoic acid (CAS 131986-05-5)
- 4-Ethyl-1-naphthoic Acid (CAS 91902-58-8)
- 7-Ethyl-1-naphthoic acid (CAS 824430-41-3)
Recommended Standards
- [3-cyano-6-(ethylamino)pyrazolo[1,5-a]pyridin-4-yl] trifluoromethanesulfonate (CAS 2649419-77-0)
- 1,4-Bisbenzil (CAS 3363-97-1)
- [1,1′-Binaphthalene]-8,8′-dicarboxylic acid (CAS 29878-91-9)
- 2-((4-Aminophenyl)thio)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 763126-91-6)
- 4-Amino-n-[1-(4-ethoxyphenyl)ethyl]butanamide hydrochloride (CAS 1384428-56-1)
- N,8-diphenyl-2,4-bis(trifluoromethyl)quinolin-7-amine (CAS 2472802-21-2)
- 4-(1-Aminoethyl)-n,n-diethylbenzene-1-sulfonamide (CAS 854035-97-5)
- 4-Chloro-2-fluoro-6-hydroxybenzaldehyde (CAS 1401251-45-3)
- 5-(Chloromethyl)pyridin-2-amine (CAS 230617-81-9)
- 1-(2-Phenylethyl)-1h-pyrazol-3-amine (CAS 876343-25-8)
- 2-(Chloromethyl)-N,N,5-trimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 1280654-95-6)
- 2-Bromotoluene-3,4,5,6-d4 (CAS 56444-57-6)
- Lovastatin Impurity 38 (CAS CATO-C4X-168438)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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