2-(Chloromethyl)-3-(4-methoxyphenyl)quinazolin-4(3H)-one CAS 22312-82-9

Description

2-(Chloromethyl)-3-(4-methoxyphenyl)quinazolin-4(3H)-one (C16H13ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

2-(Chloromethyl)-3-(4-methoxyphenyl)quinazolin-4(3H)-one (CAS 22312-82-9) is a high-purity analytical reference standard with the molecular formula C16H13ClN2O2 and a molecular weight of 300.74 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Chloromethyl)-3-(4-methoxyphenyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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