(αR)-2-Chloro-α-[[(4-methylphenyl)sulfonyl]oxy]benzeneacetic Acid Methyl Ester CAS 223123-53-3
| CAS No. | 223123-53-3 |
| Molecular Formula | C16H15ClO5S |
| Molecular Weight | 354.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (αR)-2-Chloro-α-[[(4-methylphenyl)sulfonyl]oxy]benzeneacetic Acid Methyl Ester.
(αR)-2-Chloro-α-[[(4-methylphenyl)sulfonyl]oxy]benzeneacetic Acid Methyl Ester (CAS 223123-53-3) is a high-purity analytical reference standard with the molecular formula C16H15ClO5S and a molecular weight of 354.81 g/mol.
The molecular framework of (αR)-2-Chloro-α-[[(4-methylphenyl)sulfonyl]oxy]benzeneacetic Acid Methyl Ester (C16H15ClO5S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15ClO5S |
| Molecular Weight | 354.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related R Standards
- 4-Chloro-N-(2-methoxybenzyl)-3-sulfamoylbenzamide (CAS 1110762-81-6)
- 2-Chloro-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)acetamide (CAS 116488-93-8)
- Ethyl 2-chloro-6-((4,6-dimethoxypyrimidin-2-yl)thio)benzoate (CAS 123343-07-7)
- (αR)-2-Chloro-α-[(phenylsulfonyl)oxy]-benzeneacetic Acid Ethyl Ester (CAS 1798818-13-9)
- 2-(5-Chloro-2-fluorophenyl)-N-(3-methylpyridin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (CAS 773138-62-8)
- 4-Chloro-1,3-diphenyl-1h-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 377766-08-0)
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Recommended Standards
- N-(4-(N-(5-Chloro-2-methoxyphenyl)sulfamoyl)phenyl)acetamide (CAS 196869-06-4)
- 1-(4-Chlorobenzenesulfonyl)-4-(1h-imidazole-1-carbonyl)piperazine (CAS 852840-19-8)
- Xipamide (CAS 14293-44-8)
- 2-[(2-Chlorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338396-34-2)
- 2-Isopropyl-7-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1245569-63-4)
- 5-Amino-2,3-dimethoxybenzoic acid (CAS 128670-46-2)
- 3,5-Dihydroxy-4-methoxyphenethylamine (CAS 15130-83-3)
- Pantoprazole Sodium (CAS 138786-67-1)
- 3-(4-Chloro-3-methylphenyl)propanoic acid (CAS 1086386-05-1)
- N-(4-Bromo-2-methylphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775411-20-5)
- 5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 428-22-8)
- (R)-3-Fluoropiperidine (CAS 762224-02-2)
- 6-Chloro-2-styrylquinoline (CAS 70382-82-0)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
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