5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione CAS 428-22-8

Purity 97%+In StockPharmaceutical Standards
CAS No.428-22-8
Molecular FormulaC10H9FN2O2
Molecular Weight208.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione CAS 428-22-8 chemical structure

Description

5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 428-22-8), molecular formula C10H9FN2O2 and molecular weight 208.19 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione (C10H9FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H9FN2O2
Molecular Weight208.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms2

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