Mirabegron EP Impurity F CAS 223673-34-5
| CAS No. | 223673-34-5 |
| Molecular Formula | C16H18N2O3 |
| Molecular Weight | 286.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Mirabegron EP Impurity F (CAS 223673-34-5) is a certified pharmaceutical impurity reference standard with the molecular formula C16H18N2O3 and a molecular weight of 286.33 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Mirabegron EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 286.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N2O3 |
| Molecular Weight | 286.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Nitrogen Atoms | 2 |
Related Mirabegron Standards
- Mirabegron Impurity 135 (CAS CATO-C4X-1032135)
- Mirabegron Impurity 48 (CAS CATO-C4X-103248)
- Mirabegron Impurity 85 (CAS CATO-C4X-103285)
- Mirabegron Impurity 89 (CAS CATO-C4X-103289)
- Mirabegron Impurity 114 (CAS CATO-C4X-1032114)
- Mirabegron Impurity 117 (CAS CATO-C4X-1032117)
- Mirabegron Impurity 120 (CAS CATO-C4X-1032120)
- Mirabegron Impurity 69 (CAS CATO-C4X-103269)
Recommended Standards
- Edaravone impurity 48 (CAS 87343-64-4)
- Apixaban Impurity 148 (CAS CATO-C4X-1088148)
- 4,4＇-Azoxydiphenetole (CAS 4792-83-0)
- Palbociclib Impurity 84 (CAS 571189-64-5)
- Prilocaine Impurity 15 (CAS 5602-96-0)
- Erlotinib Impurity 80 (CAS 2518426-66-7)
- Minodronic Impurity 34 (CAS 164733-64-6)
- 2-(Allylamino)benzoic acid (CAS 57397-97-4)
- 4-Hydroxy-N,N-diisopropyltryptamine (CAS 132328-45-1)
- 6-(2,2,2-Trifluoroethoxy)-3-pyridinamine (CAS 72617-82-4)
- 4-Methyl-2,5-bis(trifluoromethyl)benzamide (CAS 1807006-46-7)
- Cefdinir CP Impurity S (CAS 127770-93-8)
- Methyl 3-(cyclopent-1-en-1-yl)acrylate (CAS 54526-80-6)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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