2-Chloro-N-(3-pyridinylmethyl)nicotinamide CAS 224048-89-9
| CAS No. | 224048-89-9 |
| Molecular Formula | C12H10ClN3O |
| Molecular Weight | 247.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-N-(3-pyridinylmethyl)nicotinamide (CAS 224048-89-9) is a high-purity analytical reference standard with the molecular formula C12H10ClN3O and a molecular weight of 247.68 g/mol.
2-Chloro-N-(3-pyridinylmethyl)nicotinamide (C12H10ClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-N-(3-pyridinylmethyl)nicotinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN3O |
| Molecular Weight | 247.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 2-Chloro-N-(2-hydroxyphenyl)benzamide (CAS 20169-46-4)
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- 2-Chloro-N-(4-methylpyrimidin-2-yl)benzamide (CAS 882866-00-4)
- Triethylhexanoin (CAS 7360-38-5)
- N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamic Acid Benzyl Ester (CAS 102522-48-5)
- NU 9056 (CAS 1450644-28-6)
- 2-Iodo-1-methyl-1H-indole-3-carbonitrile (CAS 490039-77-5)
- tert-Butyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate (CAS 1186688-52-7)
- 2-(2,6-Difluorophenyl)-2-fluoroacetic acid (CAS 915030-46-5)
- N-(1-(4-Ethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-3-(furan-2-yl)-1H-pyrazol-5-yl)propionamide (CAS 1207016-86-1)
- 4-Bromo-3-chloropyridazine (CAS 1393545-85-1)
- Methyl 5-methylpicolinate (CAS 29681-38-7)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com