Allopurinol EP Impurity B CAS 22407-20-1
| CAS No. | 22407-20-1 |
| Molecular Formula | C5H6N4O2 |
| Molecular Weight | 154.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 154.13 g/mol gives Allopurinol EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Allopurinol EP Impurity B (CAS 22407-20-1, C5H6N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Allopurinol EP Impurity B (C5H6N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 154.13 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Allopurinol EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H6N4O2 |
| Molecular Weight | 154.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 4 |
Related Allopurinol Standards
- Allopurinol impurity 18 (CAS CATO-C4X-145818)
- Allopurinol impurity 12 (CAS CATO-C4X-145812)
- Allopurinol EP Impurity D (USP RC D) (CAS 1260243-04-6)
- Allopurinol EP Impurity D (CAS 19750-02-8)
- Allopurinol EP Impurity D (CAS 6994-25-8)
- Allopurinol impurity 27 (CAS CATO-C4X-145827)
- Allopurinol Impurity 31 (CAS CATO-C4X-145831)
- Allopurinol impurity 26 (CAS CATO-C4X-145826)
Recommended Standards
- Minoxidil Impurity 58 (CAS CATO-C4X-170058)
- Methotrexate Impurity 26 (CAS CATO-C4X-115426)
- Triamterene EP Impurity A (CAS 1006-23-1)
- 2-(Trifluoromethyl)pyrazine 61655-67-2 9248AB C5H3F3N2 (CAS 61655-67-2)
- Aripiprazole Impurity 49 (CAS 882880-12-8)
- Brexpiprazole Impurity 153 (CAS CATO-C4X-1131153)
- Ceftizoxime Impurity 74(isomers mixture) (CAS 94088-75-2)
- Methyl (2R,3S)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)pyrrolidine-2-carboxylate (CAS 2437327-99-4)
- 4-Tosyl-3,4-dihydro-2H-benzo[b][1,4]thiazine (CAS 338777-79-0)
- 2-Amino-4,4-difluoro-5,6-dihydro-4H-pyrazolo[1,5-d][1,4]diazepin-7(8H)-one (CAS 2409846-39-3)
- 2-Ethyl-2,3-dihydro-1h-isoindol-5-amine (CAS 1017463-79-4)
- 2,7-Diamino-9H-carbazole compd. with 2,7-dinitro-9H-carbazole (CAS 874289-93-7)
- 1-Methyl-N-(3-methylcyclopentyl)piperidin-4-amine (CAS 1344347-37-0)
- Peptide-GMF (CAS CATO-CPTD788469)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com