Ethyl 3-((tetrahydro-2h-pyran-2-yl)oxy)bicyclo[3.1.0]hexane-6-carboxylate CAS 22423-93-4
| CAS No. | 22423-93-4 |
| Molecular Formula | C14H22O4 |
| Molecular Weight | 254.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 3-((tetrahydro-2h-pyran-2-yl)oxy)bicyclo[3.1.0]hexane-6-carboxylate (CAS 22423-93-4), molecular formula C14H22O4 and molecular weight 254.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 3-((tetrahydro-2h-pyran-2-yl)oxy)bicyclo[3.1.0]hexane-6-carboxylate (C14H22O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H22O4 |
| Molecular Weight | 254.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
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Recommended Standards
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- Ebeiedinone (CAS 25650-68-4)
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- Posaconazole Impurity 264 (CAS CATO-C4X-1208264)
- (S)-2-(((tert-Butyldiphenylsilyl)oxy)methyl)pyrrolidine (CAS 209627-36-1)
- 3-(5-Bromopyridin-3-yl)propanoic acid (CAS 1022128-98-8)
- 4,7-Dihydroxyquinolin-2(1H)-one (CAS 1206788-26-2)
- 1-(2-Bromo-4-fluorobenzyl)azetidin-3-ol (CAS 1339047-73-2)
- Semaglutide Impurity 246 (CAS CATO-C4X-2226246)
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