Decitabine Alpha Isomer Impurity CAS 22432-95-7
| CAS No. | 22432-95-7 |
| Molecular Formula | C8H12N4O4 |
| Molecular Weight | 228.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 228.21 g/mol gives Decitabine Alpha Isomer Impurity distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Decitabine Alpha Isomer Impurity (CAS 22432-95-7), a pharmacopoeial impurity reference standard (molecular formula C8H12N4O4, MW 228.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Decitabine Alpha Isomer Impurity (C8H12N4O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 228.21 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Decitabine Alpha Isomer Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N4O4 |
| Molecular Weight | 228.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 4 |
Related Decitabine Standards
- Decitabine (CAS 2353-33-5)
- Decitabine Impurity 20 (CAS CATO-C4X-113720)
- Decitabine Impurity 33 (CAS CATO-C4X-113733)
- Decitabine Impurity 16 (alpha-Isomers) (CAS 570410-68-3)
- Decitabine Impurity 17 (CAS 69304-65-0)
- Decitabine Impurity 18 (CAS 178671-74-4)
- Decitabine Impurity 19 (CAS 570410-70-7)
- Decitabine impurity 32 (CAS CATO-C4X-113732)
Recommended Standards
- Istradefylline Impurity 18 (CAS 146946-10-3)
- [2-(Azidomethyl)-3-pyridinyl]-1H-imidazol-1-yl-methanone (CAS 1612756-29-2)
- Asparagine EP Impurity C (CAS 98490-54-1)
- 898790-97-1 Cyclobutyl[3-(trifluoromethyl)phenyl]methanone DTXSID00642540 (CAS 898790-97-1)
- Vonoprazan Impurity 240 (CAS CATO-C4X-1020240)
- Amisulpride Impurity 27 (CAS 1258980-24-3)
- Fludarabine Phosphate EP Impurity D (CAS 700-49-2)
- Bis-μ-chloro-tetracarbonyl dirhodium(I) (CAS 14523-22-9)
- 4-Chloro-4,4-difluoro-1-phenylbutane-1,3-dione (CAS 2062-21-7)
- 1-(N-ethylsulfamoyl)piperidine-3-carboxylic acid (CAS 1179080-56-8)
- 3-Phenyl-2-thioxo-2,3,6,7-tetrahydrothieno[3,2-d]pyrimidin-4(1H)-one (CAS 1022363-09-2)
- Ethyl 2-(2,5-dichlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylate (CAS 1431728-28-7)
- (10-(9,9-Dimethyl-9H-fluoren-2-yl)anthracen-9-yl)boronic acid (CAS 400607-35-4)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com