Fludarabine Phosphate EP Impurity D CAS 700-49-2
| CAS No. | 700-49-2 |
| Molecular Formula | C5H4FN5 |
| Molecular Weight | 153.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fludarabine Phosphate EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Fludarabine Phosphate EP Impurity D (CAS 700-49-2) is a certified pharmaceutical impurity reference standard with the molecular formula C5H4FN5 and a molecular weight of 153.12 g/mol.
Owing to a nitrile group, fluorine substitution, Fludarabine Phosphate EP Impurity D is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 153.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C5H4FN5 |
| Molecular Weight | 153.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fludarabine Standards
- Fludarabine Impurity 16 (CAS 34798-94-2)
- Fludarabine Phosphate EP Impurity B (CAS 149297-79-0)
- Fludarabine Phosphate Impurity 12 (CAS 25545-03-3)
- Fludarabine Phosphate EP Impurity H (CAS CATO-C4X-18468)
- Fludarabine Phosphate EP Impurity H (CAS 548774-57-8)
- Fludarabine Phosphate EP Impurity E (CAS 21679-14-1)
- Fludarabine Phosphate Impurity 22 (CAS 13276-42-1)
- Fludarabine Phosphate EP Impurity C Disodium Salt (CAS CATO-C4X-184621)
Recommended Standards
- 2,5-Difluoro-4-methylbenzonitrile (CAS 1003708-66-4)
- 66254-56-6 JB295061N4 1-Amino-2-methylpropylphosphonic acid, (R)- UNII-JB295061N4 Phosphonic acid, ((1R)-1-amino-2-methylpropyl)- Phosphonic acid, (1-amino-2-methylpropyl)-, (R)- (1R)-(+)-(1-Amino-2-methylpropyl)phosphonic acid (R)-alpha-Aminoisobutylphosphonic acid J550.870C (CAS 66254-56-6)
- 3,5-Difluoro-2-methylbenzonitrile (CAS 1003708-74-4)
- 35622-27-6 4-Aminobutylphosphonic acid Phosphonic acid, (4-aminobutyl)- 4-Abpa (CAS 35622-27-6)
- Acetylcysteine Impurity 29 (CAS CATO-C4X-153229)
- Ibuprofen Impurity 110 (CAS CATO-C4X-1082110)
- Bazedoxifene Acetate Impurity 8 (CAS 1802552-31-3)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-1-(2-(dimethylamino)ethyl)-5-(4-ethoxyphenyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 487020-60-0)
- (2S,4R)-rel-4-Hydroxypyrrolidine-2-carboxylic acid (CAS 618-28-0)
- 17a-Methyl-4a,5a-epoxy-17b-hydroxyandrostan-3-one (CAS 30493-58-4)
- 4-Bromo-7-chloro-1,6-naphthyridine (CAS 1378867-27-6)
- 4-(Difluoromethyl)-2-iodo-3-methyl-6-(trifluoromethoxy)pyridine (CAS 1804829-95-5)
- 2-Chloro-4,7-dimethyl-1,3-benzothiazole (CAS 80945-84-2)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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