1,3-Difluoro-2-(5-fluoro-2-nitrophenoxy)-5-(trifluoromethyl)benzene CAS 2244083-22-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2244083-22-3
Molecular FormulaC13H5F6NO3
Molecular Weight337.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,3-Difluoro-2-(5-fluoro-2-nitrophenoxy)-5-(trifluoromethyl)benzene CAS 2244083-22-3 chemical structure

Description

The occurrence of 1,3-Difluoro-2-(5-fluoro-2-nitrophenoxy)-5-(trifluoromethyl)benzene is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1,3-Difluoro-2-(5-fluoro-2-nitrophenoxy)-5-(trifluoromethyl)benzene (CAS 2244083-22-3), molecular formula C13H5F6NO3 and molecular weight 337.17 g/mol, is a CATO reference standard with documented purity and traceability.

1,3-Difluoro-2-(5-fluoro-2-nitrophenoxy)-5-(trifluoromethyl)benzene (C13H5F6NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1,3-Difluoro-2-(5-fluoro-2-nitrophenoxy)-5-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H5F6NO3
Molecular Weight337.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms1

Related Difluoro Standards

Recommended Standards

Why CATO?