2-(2-Chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene CAS 2244086-85-7
| CAS No. | 2244086-85-7 |
| Molecular Formula | C13H6ClF5O |
| Molecular Weight | 308.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(2-Chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244086-85-7), a certified reference material (molecular formula C13H6ClF5O, MW 308.63 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-Chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (C13H6ClF5O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-(2-Chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H6ClF5O |
| Molecular Weight | 308.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
Related Chlorophenoxy Standards
- 2-(3-Chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244084-63-5)
- 2-(4-Chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244087-56-5)
- 4-(4-Chlorophenoxy)-2-(methylsulfanyl)thieno[3,2-d]pyrimidine (CAS 339018-86-9)
- 3-(2-Chlorophenoxy)-6-phenylpyridazine-4-carbonitrile (CAS 338751-75-0)
- 3-(4-chlorophenoxy)-6-phenyl-4-pyridazinecarbonitrile 338751-61-4 KS-000038TF (CAS 338751-61-4)
- Methyl 3-(4-chlorophenoxy)-4-nitrobenzoate (CAS 931414-11-8)
- Methyl 4-(4-chlorophenoxy)-3-nitrobenzoate (CAS 320416-58-8)
- (E)-[2-(4-Chlorophenoxy)-1-(4-chlorophenyl)ethylidene](methoxy)amine (CAS 320422-51-3)
Recommended Standards
- n-[(5-bromothiophen-2-yl)methyl]-2-chloro-n-(prop-2-en-1-yl)acetamide (CAS 923223-48-7)
- 5-Chloro-3-(trifluoromethyl)-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid (CAS 1152979-31-1)
- 3-(4-Chloro-2-fluorophenyl)-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 114136-63-9)
- 2-Chloro-n-[2-(2,4-dichlorophenyl)pentyl]acetamide (CAS 733796-09-3)
- 3-(Benzo[d][1,3]dioxol-5-yl)-4-methyl-1H-1,2,4-triazol-5(4H)-one (CAS 108132-88-3)
- Propargyl Chloroformate (CAS 35718-08-2)
- (S)-1,1,1-Trifluoropentan-2-amine (CAS 1335661-17-0)
- Bilirubin impurity B1 (CAS CATO-C4X-15618)
- 2-Methylbenzo[d]thiazole-5,6-diamine (CAS 101258-09-7)
- 2-Fluoro-N-methylaniline (CAS 1978-38-7)
- N-(3,6-Dichloro-2-nitrophenyl)acetamide (CAS 38411-18-6)
- (S)-tert-Butyl (1-(1H-imidazol-2-yl)-2,2-dimethylpropyl)carbamate (CAS 431890-03-8)
- [6-(4-Bromophenoxy)pyridin-3-yl]methanamine (CAS 1155656-82-8)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
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