Dapoxetine Impurity 85 CAS 2245197-11-7
| CAS No. | 2245197-11-7 |
| Molecular Formula | C28H26O2 |
| Molecular Weight | 394.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapoxetine Impurity 85.
Dapoxetine Impurity 85 (CAS 2245197-11-7) is a certified pharmaceutical impurity reference standard with the molecular formula C28H26O2 and a molecular weight of 394.50 g/mol.
The molecular framework of Dapoxetine Impurity 85 (C28H26O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dapoxetine Impurity 85 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H26O2 |
| Molecular Weight | 394.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
Related Dapoxetine Standards
- Dapoxetine Impurity 55 (CAS 2242008-36-0)
- Dapoxetine Impurity 81 (CAS 2415108-74-4)
- Dapoxetine Impurity 91 (CAS CATO-C4X-143991)
- Dapoxetine Impurity 66 (CAS 864529-90-8)
- Dapoxetine Impurity 79 (CAS CATO-C4X-143979)
- Dapoxetine Impurity 68 (CAS 2716202-38-7)
- Dapoxetine Impurity 69 (CAS 1621684-78-3)
- Dapoxetine Impurity 54 (CAS CATO-C4X-143954)
Recommended Standards
- iphenhydramine Impurity 15 (CAS CATO-C4X-142415)
- Tiamulin impurity 11 (CAS CATO-C4X-221011)
- 72963-77-0 (3R,4aR,5S,6S,6aS,10aS,10bS)-3-Ethenyl-6,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate DTXSID70557531 (CAS 72963-77-0)
- Tiamulin impurity 18 (CAS CATO-C4X-221018)
- Cefixime Impurity 91 (CAS CATO-C4X-113991)
- Sitagliptin Impurity 97 (CAS 1391437-27-6)
- Encorafenib Impurity 5 (CAS CATO-C4X-32495)
- 3-Amino-5-(trifluoromethyl)pyridazine (CAS 1211591-88-6)
- 5-(2-Chlorophenyl)-1H-tetrazole (CAS 50907-46-5)
- 3-Iodo-5-methoxy-1-methyl-1H-indazole (CAS 1426424-07-8)
- Isavuconazole Impurity 27 DiHCl (CAS 2732924-99-9；2732924-98-8（free base）)
- 1-Benzyl-3-[(2,4-dimethoxyphenyl)methyl]-3-(4-iodophenyl)thiourea (CAS 306730-51-8)
- (4-(1H-1,2,3-Triazol-1-yl)piperidin-1-yl)(bicyclo[2.2.1]hept-5-en-2-yl)methanone (CAS 1795479-76-3)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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