Encorafenib Impurity 5 CAS CATO-C4X-32495
| CAS No. | CATO-C4X-32495 |
| Molecular Formula | C22H27ClFN7O5S |
| Molecular Weight | 556.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 556.01 g/mol gives Encorafenib Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Encorafenib Impurity 5 (CAS CATO-C4X-32495) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27ClFN7O5S and a molecular weight of 556.01 g/mol.
The molecular framework of Encorafenib Impurity 5 (C22H27ClFN7O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Encorafenib Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27ClFN7O5S |
| Molecular Weight | 556.01 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Encorafenib Standards
- Encorafenib Impurity 16 (CAS CATO-C4X-324916)
- Encorafenib Impurity 4 (CAS CATO-C4X-32494)
- Encorafenib (CAS 1269440-17-6)
- Encorafenib Impurity 17 (CAS CATO-C4X-324917)
- Encorafenib Impurity 2 (CAS 1269440-29-0)
- Encorafenib Impurity 12 (CAS CATO-C4X-324912)
- Encorafenib Impurity 3 (CAS CATO-C4X-32493)
- Encorafenib Impurity 14 (CAS CATO-C4X-324914)
Recommended Standards
- 2-[3-[5-Chloro-3-Ethyl-1,3-Dihydro-1-(3-Sulfopropyl)-6-(Trifluoromethyl)-2H-Benzimidazol-2-Ylidene]-1-Propen-1-Yl]-3-Ethyl-Benzoxazolium Inner Salt (CAS 83783-58-8)
- Chlorhexidine Impurity 24 (CAS CATO-C4X-225624)
- Licofelone Acyl-β-D-glucuronide (CAS 1033702-58-7)
- Chlorhexidine Impurity 36 (CAS CATO-C4X-225636)
- Ceftazidime Impurity 50 (CAS 1924627-99-5)
- Verapamil Impurity 35 HCl (CAS 77326-93-3 (free base))
- Cefixime EP Impurity E (CAS 72701-01-0)
- 1,3,3-Trimethyl-5-nitroindolin-2-one (CAS 120791-55-1)
- 2-Chloropyrido[2,3-d]pyrimidin-4(3H)-one hydrochloride (CAS 126728-21-0)
- (E)-tert-Butyl 4-(3-methoxy-3-oxoprop-1-en-1-yl)piperidine-1-carboxylate (CAS 194933-85-2)
- tert-Butyl 2-bromo-7-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 1824357-11-0)
- 3-(2-Bromoacetamido)benzene-1-sulfonyl fluoride (CAS 658-95-7)
- Perfluoro(2-methyl-3-oxahexanoyl) Fluoride (CAS 2062-98-8)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com