Pramipexole Impurity 12 CAS 2245708-68-1
| CAS No. | 2245708-68-1 |
| Molecular Formula | C10H15N3OS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pramipexole Impurity 12 (CAS 2245708-68-1) is a certified pharmaceutical impurity reference standard with the molecular formula C10H15N3OSHCl and a molecular weight of 261.77 g/mol.
Pramipexole Impurity 12 (C10H15N3OSHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pramipexole Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15N3OS HCl |
| Molecular Weight | 261.77 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pramipexole Standards
- Pramipexole Impurity 44 (CAS 1001648-65-2)
- Pramipexole USP Related Compound G (CAS 1001648-71-0)
- Pramipexole Impurity 66 (CAS 1001648-73-2)
- Pramipexole Impurity 34 (CAS 1001648-74-3)
- Pramipexole Impurity 43 (CAS 1001648-75-4)
- Pramipexole Impurity 46 (CAS 104617-49-4)
- Pramipexole Impurity 41 (CAS 104617-50-7)
- Pramipexole Impurity 17 (CAS 104617-51-8)
Recommended Standards
- Folic Acid Impurity 55 (CAS CATO-C4X-139555)
- Propofol Impurity 47 (CAS CATO-C4X-147347)
- Aztreonam impurity 66 (CAS CATO-C4X-152266)
- Letermovir impurity 55 (CAS CATO-C4X-291555)
- 1-Bromo-2,3,5-trifluoro-4-(methoxymethoxy)benzene (CAS 851341-31-6)
- Propafenone EP Impurity A (CAS 3516-95-8)
- Methyl 2-(3-bromo-1H-pyrazol-1-yl)propanoate (CAS 1823437-31-5)
- Methyl 5-amino-2,4-dimethoxybenzoate (CAS 70752-22-6)
- Tert-butyl 3-(2,4-difluorophenyl)-6,7-dihydroisoxazolo[4,3-c]pyridine-5(4H)-carboxylate (CAS 2328103-08-6)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
Why CATO?
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