N-(7-Amino-4-chloro-1-(2,2-difluoroethyl)-1H-indazol-3-yl)-N-(4-methoxybenzyl)cyclopropanesulfonamide CAS 2249975-84-4
| CAS No. | 2249975-84-4 |
| Molecular Formula | C20H21ClF2N4O3S |
| Molecular Weight | 470.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(7-Amino-4-chloro-1-(2,2-difluoroethyl)-1H-indazol-3-yl)-N-(4-methoxybenzyl)cyclopropanesulfonamide (CAS 2249975-84-4), a certified reference material (molecular formula C20H21ClF2N4O3S, MW 470.92 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(7-Amino-4-chloro-1-(2,2-difluoroethyl)-1H-indazol-3-yl)-N-(4-methoxybenzyl)cyclopropanesulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 470.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(7-Amino-4-chloro-1-(2,2-difluoroethyl)-1H-indazol-3-yl)-N-(4-methoxybenzyl)cyclopropanesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21ClF2N4O3S |
| Molecular Weight | 470.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-(1-(3-amino-4-methylphenyl)-2-oxo-1,2-dihydrobenzo[h][1,6]naphthyridin-9-yl)phenyl)methanesulfonamide (CAS 1431510-29-0)
- Ethyl 2-amino-3-(4-(5-(4-((tert-butoxycarbonyl)amino)phenyl)-1,2,4-oxadiazol-3-yl)-3-fluorophenyl)propanoate (CAS 1323994-78-0)
- Methyl 3-amino-5,6-dimethylpyrazine-2-carboxylate (CAS 6294-72-0)
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- 4-((6-Amino-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)carbamoyl)-1,2-phenylene diacetate (CAS 176379-13-8)
- 3,3’-[[2-(Cbz-amino)-2-[(2-carboxyethoxy)methyl]propane-1,3-diyl]bis(oxy)]dipropanoic Acid (CAS 200133-16-0)
- 3-Amino-6-(4-methoxyphenyl)-N-(1-phenylethyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 500272-94-6)
- 6-Amino-N-(4-bromo-2-methylphenyl)-8-(trifluoromethyl)-4-thia-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,5,7-tetraene-5-carboxamide (CAS 626228-80-6)
Recommended Standards
- 2-(4-Benzoylphenyl)-N-[(1E)-[(4-chlorophenyl)amino]methylidene]-2-(4-fluorophenyl)acetamide (CAS 860609-46-7)
- Olaparib Impurity 40 (CAS CATO-C4X-113540)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,4-difluorophenyl)acetamide (CAS 477332-63-1)
- Dacomitinib Impurity 47 (CAS CATO-C4X-208647)
- 2,2-Dimethyl-1,2,3,4-tetrahydronaphthalen-1-one (CAS 2977-45-9)
- ethyl 2-[(6-methylpyridin-3-yl)oxy]acetate (CAS 24015-97-2)
- 6-Methyl-2-phenylpyrimidine-4,5-dicarboxylic acid (CAS 61416-98-6)
- n-Methyl-4-(methylamino)butanamide hydrochloride (CAS 1121527-44-3)
- 2-((4-Methoxyphenyl)ethynyl)benzaldehyde (CAS 176910-67-1)
- 3-(6-Methoxypyridin-3-yl)-N-methylimidazo[1,2-a]pyrazin-8-amine (CAS 825630-39-5)
- 2-Ethoxy-N-(4-(methylthio)benzyl)ethan-1-amine (CAS 1154249-86-1)
- 2-(4-Fluorophenyl)pyrimidine-5-carboxylic Acid Methyl Ester (CAS 960198-50-9)
- (E)-3-(4-chloro-2-(methylsulfonyl)phenyl)acrylic acid (CAS 849035-82-1)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com