5’-Fluoro-2’-nitroacetophenone CAS 2250-48-8
| CAS No. | 2250-48-8 |
| Molecular Formula | C8H6FNO3 |
| Molecular Weight | 183.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 183.14 g/mol gives 5’-Fluoro-2’-nitroacetophenone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5’-Fluoro-2’-nitroacetophenone (CAS 2250-48-8), molecular formula C8H6FNO3 and molecular weight 183.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5’-Fluoro-2’-nitroacetophenone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6FNO3 |
| Molecular Weight | 183.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- 5-(Dimethylphosphoryl)nicotinaldehyde (CAS 2361963-21-3)
- 5-Fluoro-6-nitro-1,3-dihydroisobenzofuran (CAS 2304496-04-4)
- 4-Fluoro-2-methyl-3-nitrobenzaldehyde (CAS 861897-59-8)
- 6-(Dimethylphosphoryl)nicotinaldehyde (CAS 2624118-98-3)
- 3-(Isocyanatomethyl)-1,3-diazinane-2,4-dione (CAS 861359-45-7)
- tert-Butyl pyridin-3-ylglycinate hydrochloride (CAS 112195-03-6)
- Hydroxy-terminated poly(dimethylsiloxane) (CAS 31692-79-2)
- 6-Amino-4-(difluoromethyl)nicotinic acid (CAS 1805274-11-6)
- 3-((tert-Butoxycarbonyl)amino)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid (CAS 1206969-54-1)
- 3-(N-Methyl4-chlorobenzenesulfonamido)thiophene-2-carboxylic acid (CAS 1638612-62-0)
- 6-Hydrazinylquinoline hydrochloride (CAS 120209-22-5)
- Octadecylbenzene (CAS 4445-07-2)
- 5-Bromo-2-morpholinonicotinonitrile (CAS 1354223-80-5)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
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