5-(Dimethylphosphoryl)nicotinaldehyde CAS 2361963-21-3
| CAS No. | 2361963-21-3 |
| Molecular Formula | C8H10NO2P |
| Molecular Weight | 183.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(Dimethylphosphoryl)nicotinaldehyde (CAS 2361963-21-3) is a high-purity analytical reference standard with the molecular formula C8H10NO2P and a molecular weight of 183.14 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, 5-(Dimethylphosphoryl)nicotinaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-(Dimethylphosphoryl)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10NO2P |
| Molecular Weight | 183.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Related Dimethylphosphoryl Standards
- 2-(Dimethylphosphoryl)isonicotinaldehyde (CAS 2362014-65-9)
- 6-(Dimethylphosphoryl)nicotinaldehyde (CAS 2624118-98-3)
- 2-(Dimethylphosphoryl)benzaldehyde (CAS 2287310-50-1)
- 3-(Dimethylphosphoryl)benzaldehyde (CAS 2138040-45-4)
- 4-(Dimethylphosphoryl)benzaldehyde (CAS 2138522-51-5)
- 5-(Dimethylphosphoryl)pyrimidine-2-carbonitrile (CAS 2503202-14-8)
- 2-(Dimethylphosphoryl)ethanesulfonamide (CAS 2385358-65-4)
- 3-(Dimethylphosphoryl)picolinonitrile (CAS 2551117-29-2)
Recommended Standards
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- 2-Bromo-4,6-difluoro-1,1'-biphenyl (CAS 1428234-76-7)
- 3,3'-dioxo-[2,2'-biindolinylidene]-5,5'-disulfonic acid (CAS 483-20-5)
- 6-Bromo-2,3-difluorothioanisole (CAS 1394291-28-1)
- 1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxylic acid (CAS 929972-69-0)
- Ethyl 5-cyclohexyl-3-oxopentanoate (CAS 126930-21-0)
- 2-(Benzylamino)-N-(2-nitrophenyl)acetamide (CAS 306730-65-4)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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