Lesinurad Impurity 10 CAS 2250243-55-9

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.2250243-55-9
Molecular FormulaC18H16BrN3O4S
Molecular Weight450.31 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lesinurad Impurity 10 CAS 2250243-55-9 chemical structure

Description

As a certified reference material (CRM), Lesinurad Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies Lesinurad Impurity 10 (CAS 2250243-55-9), a pharmacopoeial impurity reference standard (molecular formula C18H16BrN3O4S, MW 450.31 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Lesinurad Impurity 10 (C18H16BrN3O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC18H16BrN3O4S
Molecular Weight450.31 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentBr-containing
Nitrogen Atoms3
Sulfur Atoms1

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