Lesinurad Impurity 8 CAS 1158970-52-5
| CAS No. | 1158970-52-5 |
| Molecular Formula | C19H18BrN3O2S |
| Molecular Weight | 432.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 432.33 g/mol gives Lesinurad Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Lesinurad Impurity 8 (CAS 1158970-52-5, C19H18BrN3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lesinurad Impurity 8 (C19H18BrN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lesinurad Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H18BrN3O2S |
| Molecular Weight | 432.33 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Lesinurad Standards
- Lesinurad Impurity 15 (CAS CATO-C4X-147815)
- lesinurad M4 metabolite (CAS 2129551-55-7)
- Lesinurad Impurity 31 (CAS 1533519-99-1)
- Lesinurad Impurity 10 (CAS 878671-99-9)
- Lesinurad Impurity 10 (CAS 2250243-55-9)
- Lesinurad Impurity 3 (CAS 1533519-96-8)
- Lesinurad Impurity 33 (CAS 1533519-94-6)
- Lesinurad Impurity 4 (CAS 1533519-97-9)
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- Flumazenil Impurity 13 (CAS CATO-C4X-143213)
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- Tert-butyl 2-(((5-bromopyridin-3-yl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 1311254-65-5)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com