Tirofiban Impurity 18 CAS 2250244-26-7
| CAS No. | 2250244-26-7 |
| Molecular Formula | C18H22N2O3 |
| Molecular Weight | 314.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tirofiban Impurity 18 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tirofiban Impurity 18 (CAS 2250244-26-7) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22N2O3 and a molecular weight of 314.38 g/mol.
Tirofiban Impurity 18 (C18H22N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22N2O3 |
| Molecular Weight | 314.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
Related Tirofiban Standards
- Tirofiban Impurity 15 (CAS CATO-C4X-125415)
- Tirofiban Impurity 42 (CAS 142374-01-4)
- Tirofiban Impurity 21 (CAS CATO-C4X-125421)
- Tirofiban Impurity 63 (CAS 158808-75-4)
- Tirofiban Impurity 118 (CAS 1346918-32-8)
- Tirofiban Impurity 23 (CAS 149490-60-8)
- Tirofiban Impurity 9 (CAS 2250244-28-9)
- Tirofiban Impurity 56 (CAS 1352839-95-2)
Recommended Standards
- Clomifene Impurity 9 (CAS 113454-71-0)
- Eltrombopag Impurity 15 (CAS CATO-C4X-119815)
- Exemestane Impurity 23 (CAS CATO-C4X-164123)
- 1,3-bis(benzyloxy)propan-2-yl acetate (CAS 137500-29-9)
- Sitagliptin Impurity 94 (CAS 881995-70-6)
- Ibuprofen EP Impurity B Sodium (CAS CATO-C4X-108236)
- Aztreonam Impurity 115 (CAS CATO-C4X-1522115)
- Tert-butyl (R)-2-isopropyl-5-oxopyrrolidine-1-carboxylate (CAS 147778-56-1)
- 2-Chloro-3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)naphthalene-1,4-dione (CAS 298215-14-2)
- (1-(Tert-butyl)-1H-pyrazol-4-yl)(1-hydroxynaphthalen-2-yl)methanone (CAS 955976-51-9)
- Minoxidil EP Impurity C (CAS 1798387-81-1)
- 2-(Carbamimidoylthio)acetic acid hydrochloride (CAS 5425-78-5)
- 1-(4-{[(1-Ethyl-pyrrolidin-2-ylmethyl)-pyridin-2-ylmethyl-amino]-methyl}-phenyl)-pyrrolidin-2-one 1667AF 883540-44-1 C24H32N4O (CAS 883540-44-1)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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