Sitagliptin Impurity 94 CAS 881995-70-6
| CAS No. | 881995-70-6 |
| Molecular Formula | C11H10F3NO2 |
| Molecular Weight | 245.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sitagliptin Impurity 94.
CATO supplies Sitagliptin Impurity 94 (CAS 881995-70-6), a pharmacopoeial impurity reference standard (molecular formula C11H10F3NO2, MW 245.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Sitagliptin Impurity 94 (C11H10F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sitagliptin Impurity 94 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10F3NO2 |
| Molecular Weight | 245.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Sitagliptin Standards
- Sitagliptin Impurity N9 (CAS 769195-26-8)
- Sitagliptin impurity 144 (CAS 881995-69-3)
- Sitagliptin Impurity 44 (CAS 1253055-92-3)
- Sitagliptin Impurity 164 (CAS 1496395-30-2)
- Sitagliptin Impurity 72 (CAS 1217854-08-4)
- Sitagliptin Impurity 138 (CAS 1283583-85-6)
- Sitagliptin Impurity 33 (CAS 936630-57-8)
- Sitagliptin Impurity 61 (CAS 1256815-03-8)
Recommended Standards
- Moxifloxacin impurity 202 (CAS 2327019-81-6)
- 2-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one (CAS 1006872-82-7)
- N-(2-oxo-2-(4-(trifluoromethyl)phenyl)ethyl)acetamide (CAS 403-34-9)
- 1-[(2R,3R,4R,5R)-5-(aminomethyl)-3-fluoro-4-hydroxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione (CAS 1012080-90-8)
- Isavuconazole Impurity 238 HCl (CAS CATO-C4X-1236238)
- Ivosidenib Impurity 3 (CAS CATO-C4X-30273)
- Pregabalin impurity 105 (CAS 616-87-5)
- Hydralazine Impurity 1 (CAS 234-80-0)
- 5-Hydroxy-1,3-dimethyl-1H-pyrazole-4-carbaldehyde (CAS 590410-65-4)
- 5-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)thiophene-2-carboxamide hydrochloride (CAS 1209773-69-2)
- tert-Butyl 3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxylate (CAS 138732-32-8)
- 4-Bromomethylpyrimidine hydrobromide (CAS 181363-06-4)
- 4-Cyclopent-1-en-1-yl-1H-pyrazol-5-amine (CAS 1257660-29-9)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com