3,3-difluoro-4,4-dimethyl-pyrrolidine;hydrochloride CAS 2253638-76-3
| CAS No. | 2253638-76-3 |
| Molecular Formula | C6H11F2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3,3-difluoro-4,4-dimethyl-pyrrolidine;hydrochloride is closely related to fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3,3-difluoro-4,4-dimethyl-pyrrolidine;hydrochloride (CAS 2253638-76-3) is a high-purity analytical reference standard with the molecular formula C6H11F2NHCl and a molecular weight of 171.62 g/mol.
The molecular framework of 3,3-difluoro-4,4-dimethyl-pyrrolidine;hydrochloride (C6H11F2NHCl) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3-difluoro-4,4-dimethyl-pyrrolidine;hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H11F2N HCl |
| Molecular Weight | 171.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related difluoro Standards
- 2-(4,5-Difluoro-2-nitrophenyl)acetic acid (CAS 1000339-22-9)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]piperazine (CAS 1000339-47-8)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]homopiperazine (CAS 1000339-49-0)
- 4,7-Difluoro-1H-indazole (CAS 1000341-68-3)
- 5,7-Difluoro-2H-indazole-3-carbaldehyde (CAS 1000343-25-8)
- 6,7-Difluoro-1H-indazol-3-ol (CAS 1000343-93-0)
- 2-(3,5-Difluoro-2-pyridyl)acetic acid (CAS 1000518-01-3)
- 2-(2,4-Difluoro-3-methylphenyl)acetic acid (CAS 1000545-11-8)
Recommended Standards
- 3-Chloro-2-cyclobutoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1352573-92-2)
- 5-Nitro-1-naphthaldehyde (CAS 6639-35-6)
- lithium(1+) ion (5S)-5-(4-fluorophenyl)-5-hydroxypentanoate (CAS 1807901-38-7)
- 5-(Difluoromethyl)-1H-imidazole-2-carbaldehyde (CAS 1780514-19-3)
- 3-Carbamoyl-5-hydroxybenzoic acid (CAS 1243392-81-5)
- Ethyl 7-Bromoisoquinoline-1-carboxylate (CAS 1823278-31-4)
- 4-bromo-5-{3,7-dioxabicyclo[4.1.0]heptan-6-yl}-1-methyl-1H-pyrazole (CAS 2031259-35-3)
- tert-Butyl 4-(6-(methoxycarbonyl)pyridin-3-yl)piperazine-1-carboxylate (CAS 1354355-85-3)
- 2,5-Dioxopyrrolidin-1-yl 6-((2,4-dinitrophenyl)amino)hexanoate (CAS 82321-04-8)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com