6,6-Difluorospiro[3.3]heptane-2-carbaldehyde CAS 2253638-83-2
| CAS No. | 2253638-83-2 |
| Molecular Formula | C8H10F2O |
| Molecular Weight | 160.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6,6-Difluorospiro[3.3]heptane-2-carbaldehyde is closely related to a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6,6-Difluorospiro[3.3]heptane-2-carbaldehyde (CAS 2253638-83-2) is a high-purity analytical reference standard with the molecular formula C8H10F2O and a molecular weight of 160.16 g/mol.
Structurally, 6,6-Difluorospiro[3.3]heptane-2-carbaldehyde (C8H10F2O) contains a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 160.16 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10F2O |
| Molecular Weight | 160.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Difluorospiro Standards
- 1,1-Difluorospiro[2.5]octan-6-one (CAS 1513853-81-0)
- 6,6-Difluorospiro[2.5]octan-1-amine (CAS 1461706-22-8)
- (2,2-Difluorospiro[3.3]heptan-6-yl)methanamine (CAS 1638920-27-0)
- 1,1-Difluorospiro[2.5]octan-6-amine (CAS 1782325-38-5)
- 1-(1,1-Difluorospiro[2.3]Hexan-5-yl)-N-methylmethanamine (CAS 2092713-01-2)
- 1,1-Difluorospiro[2.5]Octan-5-amine (CAS 2306264-20-8)
- 2,2-Difluorospiro[2.3]Hexane-1-carboxylic acid (CAS 1936230-67-9)
- 1,1-difluorospiro[2.3]hexane-5-carboxylic acid (CAS 1955514-17-6)
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