2-(2-Chloro-5-nitrophenyl)pyridine hydrochloride CAS 2254573-75-4
| CAS No. | 2254573-75-4 |
| Molecular Formula | C11H7ClN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2-Chloro-5-nitrophenyl)pyridine hydrochloride (CAS 2254573-75-4), molecular formula C11H7ClN2O2HCl and molecular weight 271.10 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(2-Chloro-5-nitrophenyl)pyridine hydrochloride (C11H7ClN2O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 271.10 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClN2O2 HCl |
| Molecular Weight | 271.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 3-[(2-Chloro-4-methylsulfonyl)phenoxy]benzoic acid (CAS 1000018-31-4)
- 6-Chloro-2-[2-(3-[(6-chloro-1-ethylbenz[c,d,]indole-2[1H]-ylidene)ethylidene]-2-phenyl-1-cyclopenten-1-yl)ethenyl]-1-ethylbenz[c,d]indolium tetrafluoroborate (CAS 100012-45-1)
- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
- (3-Chloro-2-fluoro-5-iodophenyl)methanol (CAS 1000162-10-6)
- 3-Chloro-2-fluoro-5-nitrobenzoic acid (CAS 1000162-34-4)
- 2-Chloro-N-(piperidin-4-yl)-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-amine hydrochloride (CAS 1000207-51-1)
- 4-chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine (CAS 1000303-40-1)
Recommended Standards
- 5-bromo-2-hydroxy-3-nitropyridine (CAS 15862-34-7)
- PEg6-(ch2co2t-butyl)2 (CAS 211746-79-1)
- 2-Propoxyaniline Hydrochloride (CAS 220594-10-5)
- 3-(3-Ethyl-1-methyl-1h-1,2,4-triazol-5-yl)aniline (CAS 1342034-23-4)
- potassium 5-ethyl-1,2,4-oxadiazole-3-carboxylate (CAS 1803591-86-7)
- Valsartan Impurity 72 (CAS 601-77-4)
- Tert-butyl ((5,6-dimethoxypyridin-2-yl)methyl)carbamate (CAS 1142192-08-2)
- Abrocitinib Impurity 14-d4 (CAS CATO-C4X-288414)
- N-allyl-7,9-dimethyl-2-((4-methylbenzyl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine (CAS 672950-71-9)
- Compstatin control peptide (CAS 301544-78-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com