5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine CAS 2263-96-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2263-96-9
Molecular FormulaC11H8ClF3N4
Molecular Weight288.66 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine CAS 2263-96-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 288.66 g/mol gives 5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine (CAS 2263-96-9), a certified reference material (molecular formula C11H8ClF3N4, MW 288.66 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 288.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H8ClF3N4
Molecular Weight288.66 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/Cl-containing
Nitrogen Atoms4

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