4-(4-Chlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine CAS 861451-58-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Chlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine.

4-(4-Chlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 861451-58-3) is a high-purity analytical reference standard with the molecular formula C11H8ClF3N4 and a molecular weight of 288.66 g/mol.

4-(4-Chlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (C11H8ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(4-Chlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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