2-(Trifluoromethyl)-6,9-dihydro-1h-purin-6-one CAS 2268-14-6
| CAS No. | 2268-14-6 |
| Molecular Formula | C6H3F3N4O |
| Molecular Weight | 204.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Trifluoromethyl)-6,9-dihydro-1h-purin-6-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(Trifluoromethyl)-6,9-dihydro-1h-purin-6-one (CAS 2268-14-6), molecular formula C6H3F3N4O and molecular weight 204.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-(Trifluoromethyl)-6,9-dihydro-1h-purin-6-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H3F3N4O |
| Molecular Weight | 204.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine (CAS 1030420-77-9)
- 5-(Trifluoromethyl)oxazolo[4,5-b]pyridin-2(3H)-one (CAS 1092569-13-5)
- 3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazin-8(7H)-one (CAS 140911-30-4)
- 5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one (CAS 40775-91-5)
- 5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one (CAS 299918-83-5)
- 7-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one (CAS 244220-25-5)
- 8-(trifluoromethyl)-6,7-dihydro-1H-purin-6-one (CAS 2268-13-5)
- 4-(Trifluoromethyl)benzo[d][1,3]dioxol-2-one (CAS 933674-86-3)
Recommended Standards
- (1R,5S)-3-bromo-8-methyl-8-azabicyclo[3.2.1]Octane (CAS 27809-79-6)
- 2-Bromo-3-(piperidin-1-yl)prop-1-ene (CAS 37828-88-9)
- 4-Bromobicyclo[2.2.2]octan-1-amine (CAS 135908-39-3)
- 4-Bromobicyclo[2.2.2]octan-1-amine (CAS 135908-36-0)
- 3-Amino-2-(4-chlorophenyl)propan-1-ol hydrochloride (CAS 1280721-64-3)
- 2-(4,5-Dimethyl-1-oxo-7-(1h-pyrrol-1-yl)furo[3,4-d]pyridazin-2(1h)-yl)acetic acid (CAS 885524-29-8)
- 2-(4-Bromo-2-fluorophenyl)-2-methylpropanoic acid (CAS 1314671-09-4)
- 1,4-Bis(di-i-propylphosphino)butane, min. 98% (CAS 80499-19-0)
- (4-tert-butyl-1,3-oxazol-2-yl)methanol (CAS 1783776-09-9)
- (5S)-5-[(1R)-1-Aminoethyl]-2-pyrrolidinone (CAS 2409830-34-6)
- 2-Bromo-3-phenylacrylic acid (CAS 1727-53-3)
- 5-(Cyclopropylmethoxy)-2-fluoropyridine (CAS 213765-91-4)
- (R)-Benzyl 2-((tert-butoxycarbonyl)amino)-3-(3-iodo-4-methoxyphenyl)propanoate (CAS 1263377-25-8)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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