[3-Cyano-4-(trifluoromethoxy)phenyl]boronic acid CAS 2268800-99-1
| CAS No. | 2268800-99-1 |
| Molecular Formula | C8H5BF3NO3 |
| Molecular Weight | 230.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[3-Cyano-4-(trifluoromethoxy)phenyl]boronic acid (C8H5BF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
[3-Cyano-4-(trifluoromethoxy)phenyl]boronic acid (CAS 2268800-99-1) is a high-purity analytical reference standard with the molecular formula C8H5BF3NO3 and a molecular weight of 230.94 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures [3-Cyano-4-(trifluoromethoxy)phenyl]boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BF3NO3 |
| Molecular Weight | 230.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyano Standards
- (5-Cyano-2-(trifluoromethoxy)phenyl)boronic acid (CAS 1072946-64-5)
- 4-Cyano-6-iodopyrimidine (CAS 1806269-00-0)
- (2-Cyano-4-(piperazin-1-yl)phenyl)boronic acid (CAS 2225155-93-9)
- 3-Cyano-5-(trifluoromethoxy)benzoic acid (CAS 453565-91-8)
- (2Z)-2-Cyano-3-[(4-methoxyphenyl)amino]but-2-enamide (CAS 120651-01-6)
- 6-Cyano-4-cyclopropoxy-N,N-dimethylpicolinamide (CAS 1243364-16-0)
- 4-Cyano-5-cyclopropoxy-N,N-dimethylnicotinamide (CAS 1243399-63-4)
- 6-Cyano-3-cyclopropoxy-N,N-dimethylpicolinamide (CAS 1243402-99-4)
Recommended Standards
- 3-(Bromomethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 1609396-23-7)
- Bis(2-bromoethyl)amine (CAS 3890-99-1)
- (2-Cyclopropyl-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 1446486-08-3)
- 1,1,1,3,3,3-Hexafluoro-2-bromo-propane (CAS 2252-79-1)
- Nickel antimonide (CAS 12503-49-0)
- 5-Amino-2-morpholinobenzoic acid (CAS 65989-45-9)
- Bis(4-methoxybenzyl)amine (CAS 17061-62-0)
- 5-Hydrazinyl-3-(methylthio)isothiazole-4-carbonitrile (CAS 29231-68-3)
- 4-Amino-1-azabicyclo[2.2.1]heptane Dihydrochloride (CAS 1338705-69-3)
- (Z)-2-Propylpent-3-enoic Acid (CAS 90830-42-5)
- 4-Hydroxythiophene-2-carbonitrile (CAS 256495-21-3)
- Tocopherol Impurity 20 (CAS 7695-91-2)
- 3-(5-Chlorothiophen-2-yl)-3-hydroxypropanenitrile (CAS 1525651-17-5)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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